Andy Oxman by National Elf Service published on 2018-09-17T10:57:41Z Research Director of the Global Health Unit at the Norwegian Institute of Public Health, talking about the Informed Health Choices project and Key Concepts for critical thinking about treatment claims. https://en.testingtreatments.org/key-concepts-for-assessing-claims-about-treatment-effects/ Lancet papers Nsangi A, Semakula D, Oxman A et al. Effects of the Informed Health Choices primary school intervention on the ability of children in Uganda to assess the reliability of claims about treatment effects: a cluster-randomised controlled trial Lancet 2017; 390:374-88 https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(17)31226-6/fulltext Semakula D, Nsangi A, Oxman A et al. Effects of the Informed Health Choices podcast on the ability of parents of primary school children in Uganda to assess claims about treatment effects: a randomised controlled trial Lancet 2017; 390:389-98 https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(17)31225-4/abstract An N of 1 trial is a trial with just one person where you randomly decide which treatment is given when. For example, a medicine versus a placebo and you alternate that, usually for up to three times per treatment. The big advantage of this is you find out for that person whether the treatment is helpful or harmful. The limitation of n-of-1-trial isthat you can only use it for diseases that are chronic and stable and where you go more or less go back to the state you were in to begin with after the treatment. So it's good for treatment of symptoms but not fora cure for the disease. GETIT entry: http://www.getitglossary.org/term/single+participant+trial Genre Science
