Between 1985 and 1995, Marco Messina has played in many Clubs. In 1991, he founded the band 99 Posse. Since then, the band has sold 500,000 copies of their 5 albums.

In 2001 Marco teamed up with 99 POSSE singer Meg, as ‘NOUS’, to create a soundtrack for the theatre production of ‘Dentro la Tempesta’, directed by Cauteruccio, later released on CD as La Tempesta..

In 2003, Marco teamed up with Lino Monaco and Nicola Buono of the Italian electronic duo Retina.it, to create the independent music label Mousikelab. In 2004, they formed the trio RESINA, releasing the much acclaimed album 'Opinio omnium'.

He composed, with Massimiliano Sacchi, the score of 'La bocca del lupo’ directed by Pietro Marcello and produced by Indigo Film. The film wins David di Donatello (best documentary) ed il Torino Film Festival (best film)

Marco Messina has collaborated with the following artists and musicians: Pino Daniele, Subsonica, Meg, Raiz, Alma Megretta, General Levy,Linton Kwesi Johnson, Dennis Bovell, 24 Grana, Solis String Quarte, Danilo Vigorito, Peppe Voltarelli, Roy Pacy, Her, Barbara de Dominicis, Speaker Cenzou, Papa J, Vladimir Luxuria, Retina.It, Bruno B, Maurizio Capone, Mandara, Mirko Signorile, Ringe Ringe Raja, Nino Bruno, Costanza; Abel Ferrara

He’ s running a recording studio: mousikelab studio

Soundtracks and Soundesign (film):
1993 – Sud (regia G. Salvatores)
2005 – Tree ‘r us (regia L. Curto)
2007 – Il passaggio della linea (regia P. Marcello)
2009 – Una montagna di balle (regia N. Angrisano)
2009 – La bocca del Lupo (regia P. Marcello)
2010 – Napoli 24h
2011 – Il Silenzio di Pelešjan (regia P. Marcello)

Soundtracks and Soundesign (TV):
2009 – "Dark Blue”, Episode 106
2010 – “CSI” Season 10, Episode 1016
2010 – "The L Word" Season 06, Episode 08

Soundtracks and Soundesign (theatre):
2002 – La Tempesta (director G. Cauteruccio)
2003 – Iconoclast (director F. Cauteruccio)
2003 – aIds: storie d’ Impero applicato (director E. Morrone)
2004 – Capita (director L. Curto)
2007 – A Global Dionysus in Napoli (director OPS)
2008 – Petrolio (director F. Saponaro)
2008 – Questa corte condanna (director M. Anselmo)
2008 – On Off (director MC Barberio)
2009 – Superwoobinda (director M. Nappo)
2009 – Padiglione Sorveglianza (director D. Sabino)
2009 – Made in Naples (director Carol Armitage)
2010 – Desurrezione (director Alessandra Cutolo)

Discography:
as 99 posse:
1992 – Rafaniello/Salario Garantito
1993 – Curre curre guagliò
1995 – Guai a chi ci tocca
1996 – Cerco tempo
1998 – Corto circuito
2000 – LA vida que vendrà
2001 – NA9910°
2011 – Cattivi Guagliuni

1992 – Itaian Posse I (compilation)
1992 – Notte di rime dirette (compilation)
1993 – Italian Posse II (compilation)
1993 – Live al Faro (Ricomincio dal Faro autoproduzioni)
1993 – Senza tetto non ci sto (compilation)
1993 – Camminare sotto il cielo di notte (compilation)
1993 – Sud (colonna sonora originale del film di Gabriele Salvatores)
1994 – Hokahey (compilation)
1994 – L’ Italia del rock N°12 (compilation)
1994 – Cantanapoli Antifascista (compilation)
1995 – Rap Rap Rappresaglia (compilation)
1997 – Cuore Nero (album di Franco Ricciardi)
1999 – Onda d’ Urto (compilation)
2001 – Medina (Pino Daniele)

as Nous:
2002 – La Tempesta

as Resina:
2003 – opinio omnium

as Pentole & Computer:
2004 – Condominium (compilation)
2004 – GE-2001 (compilation)

as B_co.me:
2008 – Elettrowave v. 08 (compilation)

as Kyò:
2010 – Kyò

mix, productions and remixes:
1994 – Speaker Cenzou, Il bambino cattivo (production, programming, mix)
1996 – Malastrada, (production, programming, mix)
2000 – Vladimir Luxuria (remix)
2001 – Solis Strinq Quartet (remix)
2001 – 24 Grana, Stai mai ‘cca (remix)
2004 – Mandara , Alatul (mix)
2004 – Chop Chop Band, Ci sei o no? (mix)
2004 – Plastica (mix)
2004 – Meg, Meg (programming e mix)
2004 – Meg, Simbiosi (remix)
2004 – Roy Paci (remix)
2006 – Parto delle Nuvole Pesanti (programming)
2008 – Spaccanapoli (mix)
2008 – Mandara (mix)
2008 – Mirko Signorile (mix/programming)
2008 – Barbara de Dominicis, Antigone (mix e programming)
2008 – Ringe Ringe Raia (mix)
2008 – Nino Bruno e le 8 tracce (mix)
2009 – Superlowed (mix)

Collaborations:
Pino Daniele, Subsonica, Meg, Raiz, Alma Megretta, General Levy, Linton Kwesi Johnson, Dennis Bovell, 24 Grana, Solis String Quartet, Danilo Vigorito, Peppe Voltarelli, Roy Pacy, Her, Barbara de Dominicis, Speaker Cenzou, Vladimir Luxuria, Retina.It, Maurizio Capone, Mandara, Mirko Signorile, Ringe Ringe Raia, Nino Bruno, Costanza, Marcello Colasurdo

Prize
1994 – Targa Tenco per la “Miglior opera in dialetto” with Curre curre guagliò
2000 – Targa Tenco per la “Miglior opera in dialetto” with La vide que vendrà